KMC researchers come with surprise findings

KMC researchers come with surprise findings

Mangalore Today News Network

Udupi, Nov 25, 2016: Manipal University research came up with more surprise findings; led by Dr Satish Adiga, Head of the Department of Clinical Embryology, Kasturba Medical College (KMC), Manipal, and Hanudatta Atreya of Indian Institute of Science (IISc), Bengaluru, identified a way to predict DNA defects in IVF derived early embryos using a noninvasive technology.

A press release issued here on Nov 24,  Thursday said that ‘Scientific Reports,’ a British journal from Nature Group, published this innovative finding. In this study, the researchers induced DNA lesions experimentally in mouse embryos and observed stark changes in embryo metabolism with high level of DNA damage.

The researchers could detect this change 24 hours before the onset of cell death in the embryos. This may prove to be advantageous when extrapolated to the clinical IVF set up. The team included Fiona D’Souza, Shubhashree Uppangala, Guruprasad Kalthur and Sudeep Salian from KMC, and scientists from IISc and National Centre for Biological Sciences, Bengaluru.